
HYPO21
Biomimetic by Design. Minimal by Nature
HYPO21 is made of Pure Hypochlorous (HOCl). Hypochlorous acid (HOCl) is a naturally occurring molecule produced by white blood cells as part of the body’s innate immune response, where it plays a key role in regulating microbial balance and inflammatory signalling. Because HOCl is something the body already produces and recognises, it is inherently compatible with the skin. HYPO21 is a biomimetic formulation, meaning it is designed to mimic this natural biological process by delivering highly purified, stabilised HOCl in a skin-physiological form. Rather than introducing foreign or aggressive actives, HYPO21 works in harmony with the skin’s natural defence and repair mechanisms, supporting balance, tolerance, and barrier integrity.
Minimal. Pure. Clinically Assessed.
HYPO21 is formulated using only essential, skin-physiological components, designed to support the skin’s natural balance and barrier function.
The formulation has been clinically assessed for skin tolerance and performance in human participants.
What is Hypochlorous Acid (HOCl)?
Hypochlorous acid (HOCl) is a naturally occurring molecule produced by white blood cells as part of the body’s innate immune response.
In skincare, Pure HOCl is valued for its ability to support microbial balance and help calm visible skin inflammation without disrupting healthy tissue.
HYPO21 uses high-purity, stabilised HOCl in a form that is recognised and well tolerated by the skin.
How Does HOCl Support the Skin?
HOCl helps create an environment that supports:
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A balanced skin microbiome
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Reduced visible redness and irritation
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Improved comfort in sensitised or compromised skin
It works with the skin’s natural processes, rather than overriding them with harsh actives.
Clinical Assessment Summary
HYPO21 Skin Spray underwent a 12-week multicentre clinical assessment involving 100 participants with acne, eczema, psoriasis, and rosacea, using twice-daily application.
The assessment showed:
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High levels of skin tolerance
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Visible improvement across all skin groups
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High user satisfaction and ease of use
The formulation was also found to be suitable for sensitive, inflamed, or compromised skin
Skin Barrier & Inflammatory Markers
During clinical assessment, HYPO21 demonstrated:
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Reduced bacterial load on the skin
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Reduction in key inflammatory markers including IL-1, IL-6, and TNF-alpha
These findings are consistent with HOCl’s role in supporting cutaneous homeostasis.
pH-Controlled, Skin-Physiological Formulation
HYPO21 is formulated within a skin-physiological pH range, which is essential for:
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Maintaining skin barrier integrity
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Reducing the risk of stinging or irritation
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Ensuring HOCl stability
This contributes to the formulation’s suitability for daily and professional use.
What HYPO21 Does NOT Contain
HYPO21 is intentionally free from ingredients that may compromise the skin barrier:
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No alcohol
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No fragrance or essential oils
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No preservatives
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No phosphoric acid
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No harsh disinfectants
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No unnecessary additives
This minimal approach supports use on sensitive and post-procedure skin.
Ingredient Transparency
HYPO21 is committed to:
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Minimal, purpose-driven formulations
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Clinically note-worthy skin tolerance
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Clear, responsible ingredient communication
Every ingredient is present to support the skin, and nothing more.
We believe that making small changes can make a big difference.
Choosing Natural products that are good for your skin and for our planet is what we do best.
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Our HOCl is formulated to the same pH as your skin and is the ideal soothing, purifying and protecting solution for your skin.
HYPO21 Contains NO Sodium Hypochlorite, Phosphoric Acid or Alcohol
Q&A
Is HYPO21 safe for sensitive or compromised skin?
Yes. HYPO21 is suitable for:
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Sensitive skin
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Post-procedure skin
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Inflamed or compromised skin barriers
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Skin prone to redness or irritation
It is non-toxic, non-irritating, alcohol-free, and fragrance-free, making it safe for daily use.
Does HYPO21 sting or burn when applied?
No. A properly purified HOCl solution should not sting.
If a hypochlorous product causes discomfort, it is often a sign of:
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Poor formulation
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Incorrect pH
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Impurities left behind during production
HYPO21 has been developed to remain gentle yet effective, even on broken or sensitised skin.
Is HYPO21 Antibacterial?
Yes, HOCl is naturally antimicrobial and helps reduce harmful bacteria on the skin without disrupting beneficial microbes.
Unlike harsh antiseptics, HYPO21 does not strip or damage the skin barrier.
