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Hypochlorous Acid (HOCl): An Important Emerging Option for Periprocedural Care.

Updated: Nov 24, 2021

HYPO21 Skin Spray produces a range of topical HOCl products that have broad utility for aesthetic procedures. These are available for in-office use by the surgeon and can also be dispensed through the practice for home use.

HYPO21 Skin Spray

Pre-procedure use: A spray formulation, such as HYPO21 Skin Spray Spray, is especially useful before a procedure to prep the surgical site and eliminate surface bacteria. The spray is easy to apply directly to the site and can simply be left on the skin. However, it is beneficial to also use a gauze pad to wipe the skin after application (spray the gauze with additional product), to mechanically remove bacteria and biofilm. An added benefit of this mechanical cleansing is that it will also remove any residual make-up or topically applied products that may not be readily removed with soap-and-water cleansing.

In addition,The magic ingredient of HYPO21 Skin Spray is HOCL. HOCl also works as an anti-inflammatory and increases blood flow to enhance healing.

Post-procedure: HYPO21 Skin Spray pure formulations means it can be applied immediately after any procedure and through the healing phase. A benefit of the pure formulation is that they can be readily applied to tender skin without requiring that patients touch a healing wound site. HYPO21 Skin Spray can be added to the wound site immediately post-procedure to protect the wound from Biofilm, Bacteria and Infection and also to give extra re-hydration to skin. Another aspect of wound healing is scar prevention. Especially in individuals with a history of scarring and especially hypertrophic scarring, strategies to reduce scar formation are a primary focus.


Even as technical advancement and new technologies have led to less invasive surgical approaches and barely-invasive cosmetic interventions, optimal wound healing remains a primary concern for surgeons and patients. HOCl has emerged as an important and convenient option for use in the peri-procedural period and for scar management. Its range of effects—antimicrobial, anti-inflammatory, and anti-pruritic—and its ability to support healthy skin healing makes it an ideal agent for use in the aesthetic practice.

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